Advances in Nanomedicine for Targeted Drug Delivery and Imaging

Abstract

Nanomedicine has emerged as a promising approach for revolutionizing drug delivery and imaging in biomedical applications. This review highlights recent advances in nanotechnology-enabled strategies for targeted drug delivery and imaging, focusing on their potential for enhancing therapeutic efficacy and diagnostic accuracy. Nanoparticles, liposomes, dendrimers, and polymeric micelles are among the versatile nanocarriers explored for encapsulating and delivering therapeutic agents to specific sites within the body. Furthermore, the integration of imaging modalities such as magnetic resonance imaging (MRI), computed tomography (CT), and fluorescence imaging with nanocarrier systems enables real-time visualization and monitoring of drug distribution and therapeutic response. Targeting ligands, stimuli-responsive nanomaterials, and surface engineering techniques enhance the specificity and selectivity of nanocarriers, allowing precise delivery of therapeutics to diseased tissues while minimizing off-target effects. Additionally, advances in nanotechnology have led to the development of theranostic platforms capable of combining diagnostic imaging and therapeutic functionalities within a single nanocarrier. The synergistic integration of nanomedicine with precision medicine holds great promise for personalized healthcare by enabling tailored treatment regimens and optimizing patient outcomes.