The Gut Microbiome and its Influence on Immune Function: A Comprehensive Review

Abstract

The gut microbiome plays a pivotal role in regulating immune function and maintaining host health. This comprehensive review provides an overview of the complex interactions between the gut microbiome and the immune system, highlighting the mechanisms by which gut microbes influence immune function and contribute to both health and disease. Key topics covered include the development of the gut microbiome during early life, the establishment of immune tolerance, the modulation of immune responses by gut microbes, and the role of dysbiosis in immune-mediated disorders. Additionally, the review explores the potential therapeutic interventions targeting the gut microbiome to modulate immune function and improve health outcomes. Understanding the intricate crosstalk between the gut microbiome and the immune system is essential for elucidating disease pathogenesis and developing novel strategies for immune modulation and disease management.